Drug interactions
Moxifloxacin + Vildagliptin
Severity: Minor
Moxifloxacin and Vildagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fluoroquinolones can disturb glucose homeostasis and cause either hypoglycemia or hyperglycemia, particularly in diabetic patients. When given with a glucose-lowering agent such as vildagliptin, glycemic control may become less predictable. Moxifloxacin carries a lower dysglycemia risk than some other quinolones, and vildagliptin alone rarely causes hypoglycemia.
What this interaction means in plain words
Moxifloxacin and Vildagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Moxifloxacin belongs to Anti Bacterial; Vildagliptin belongs to Endocrine.
Why it happens
Fluoroquinolones affect pancreatic beta-cell insulin release, producing additive or unpredictable effects on glucose with antidiabetic drugs.
What to do
Counsel the patient to recognize symptoms of low and high blood glucose and check blood glucose more often during the antibiotic course. Switch to a non-quinolone antibiotic if dysglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Other interactions of Vildagliptin
- Ciprofloxacin + Vildagliptin Moderate
- Deflazacort + Vildagliptin Moderate
- Dexamethasone + Vildagliptin Moderate
- Gemifloxacin + Vildagliptin Moderate
- Glimepiride + Vildagliptin Moderate
- Hydrochlorothiazide-lisinopril + Vildagliptin Moderate
Frequently asked questions
Can I take Moxifloxacin with Vildagliptin?
MediHelp rates the interaction as minor. Moxifloxacin and Vildagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fluoroquinolones can disturb glucose homeostasis and cause either hypoglycemia or hyperglycemia, particularly in diabetic patients. When given with a glucose-lowering agent such as vildagliptin, glycemic control may become less predictable. Moxifloxacin carries a lower dysglycemia risk than some other quinolones, and vildagliptin alone rarely causes hypoglycemia.
How serious is the interaction between Moxifloxacin and Vildagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient to recognize symptoms of low and high blood glucose and check blood glucose more often during the antibiotic course. Switch to a non-quinolone antibiotic if dysglycemia occurs.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
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