Drug interactions
Porfimer + Verapamil
Severity: Minor
Porfimer and Verapamil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium channel blockers have been proposed to reduce the effect of photodynamic therapy with porfimer by affecting vascular response or drug uptake. The clinical importance is uncertain.
What this interaction means in plain words
Porfimer and Verapamil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Porfimer belongs to Miscellaneous; Verapamil belongs to Cardiovascular.
Why it happens
Mechanism not established; possible alteration of tumor vascular response to photodynamic therapy.
What to do
Be aware that treatment response may be reduced; assess response to photodynamic therapy and consider timing if the verapamil is not essential.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Verapamil
- Dofetilide + Verapamil Contraindicated
- Flibanserin + Verapamil Contraindicated
- Lomitapide + Verapamil Contraindicated
- Lonafarnib + Verapamil Contraindicated
- Pimozide + Verapamil Contraindicated
- Acebutolol + Verapamil Major
Other interactions of Porfimer
Frequently asked questions
Can I take Porfimer with Verapamil?
MediHelp rates the interaction as minor. Porfimer and Verapamil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium channel blockers have been proposed to reduce the effect of photodynamic therapy with porfimer by affecting vascular response or drug uptake. The clinical importance is uncertain.
How serious is the interaction between Porfimer and Verapamil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Be aware that treatment response may be reduced; assess response to photodynamic therapy and consider timing if the verapamil is not essential.
What other medicines interact with Verapamil?
MediHelp also lists interactions of Verapamil with, for example, Dofetilide, Flibanserin, Lomitapide. The full list is on the Verapamil page.
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