Drug interactions
Prochlorperazine + Teduglutide
Severity: Minor
Prochlorperazine and Teduglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Teduglutide improves intestinal fluid and nutrient absorption and may therefore increase absorption of oral drugs such as prochlorperazine. This could raise prochlorperazine exposure and produce more sedation or extrapyramidal effects.
What this interaction means in plain words
Prochlorperazine and Teduglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Prochlorperazine belongs to Central Nervous System; Teduglutide belongs to Endocrine.
Why it happens
Teduglutide enhances intestinal absorptive capacity, potentially increasing oral bioavailability of co-administered drugs.
What to do
Monitor for increased prochlorperazine effects when teduglutide is started and adjust the dose if adverse effects appear.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Prochlorperazine
- Dronedarone + Prochlorperazine Contraindicated
- Ibutilide + Prochlorperazine Contraindicated
- Nilotinib + Prochlorperazine Contraindicated
- Pimozide + Prochlorperazine Contraindicated
- Prochlorperazine + Thioridazine Contraindicated
- Amiodarone + Prochlorperazine Major
Other interactions of Teduglutide
- Chlordiazepoxide + Teduglutide Moderate
- Clonazepam + Teduglutide Moderate
- Colchicine + Teduglutide Moderate
- Cyclosporin + Teduglutide Moderate
- Digoxin + Teduglutide Moderate
- Ethosuximide + Teduglutide Moderate
Frequently asked questions
Can I take Prochlorperazine with Teduglutide?
MediHelp rates the interaction as minor. Prochlorperazine and Teduglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Teduglutide improves intestinal fluid and nutrient absorption and may therefore increase absorption of oral drugs such as prochlorperazine. This could raise prochlorperazine exposure and produce more sedation or extrapyramidal effects.
How serious is the interaction between Prochlorperazine and Teduglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for increased prochlorperazine effects when teduglutide is started and adjust the dose if adverse effects appear.
What other medicines interact with Prochlorperazine?
MediHelp also lists interactions of Prochlorperazine with, for example, Dronedarone, Ibutilide, Nilotinib. The full list is on the Prochlorperazine page.
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