Skip to content

Drug interactions

Prochlorperazine + Teduglutide

Severity: Minor

Prochlorperazine and Teduglutide: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Teduglutide improves intestinal fluid and nutrient absorption and may therefore increase absorption of oral drugs such as prochlorperazine. This could raise prochlorperazine exposure and produce more sedation or extrapyramidal effects.

What this interaction means in plain words

Prochlorperazine and Teduglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Prochlorperazine belongs to Central Nervous System; Teduglutide belongs to Endocrine.

Evidence level: Low

Why it happens

Teduglutide enhances intestinal absorptive capacity, potentially increasing oral bioavailability of co-administered drugs.

What to do

Monitor for increased prochlorperazine effects when teduglutide is started and adjust the dose if adverse effects appear.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ members

Unlock the full page

Create an account and start a Pro+ trial to unlock the full management advice for Prochlorperazine and Teduglutide, the additional notes, the evidence detail and the whole-prescription interaction checker.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Try Pro+ free for 7 days on the web. No card needed.

Frequently asked questions

Can I take Prochlorperazine with Teduglutide?

MediHelp rates the interaction as minor. Prochlorperazine and Teduglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Teduglutide improves intestinal fluid and nutrient absorption and may therefore increase absorption of oral drugs such as prochlorperazine. This could raise prochlorperazine exposure and produce more sedation or extrapyramidal effects.

How serious is the interaction between Prochlorperazine and Teduglutide?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for increased prochlorperazine effects when teduglutide is started and adjust the dose if adverse effects appear.

What other medicines interact with Prochlorperazine?

MediHelp also lists interactions of Prochlorperazine with, for example, Dronedarone, Ibutilide, Nilotinib. The full list is on the Prochlorperazine page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug interactions

Get the app Sign in