Drug interactions
Silodosin + Treprostinil
Severity: Minor
Silodosin and Treprostinil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Treprostinil is a potent vasodilator and may add to the blood pressure lowering of silodosin. Patients may experience symptomatic hypotension, dizziness or syncope.
What this interaction means in plain words
Silodosin and Treprostinil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Silodosin belongs to Genitourinary; Treprostinil belongs to Cardiovascular.
Why it happens
Additive vasodilatory pharmacodynamic effects of a prostacyclin analogue and an alpha-1 blocker.
What to do
Monitor blood pressure and orthostatic symptoms when starting or adjusting either drug.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Silodosin
- Atazanavir + Silodosin Contraindicated
- Conivaptan + Silodosin Contraindicated
- Darunavir + Silodosin Contraindicated
- Fosamprenavir + Silodosin Contraindicated
- Indinavir + Silodosin Contraindicated
- Itraconazole + Silodosin Contraindicated
Other interactions of Treprostinil
Frequently asked questions
Can I take Silodosin with Treprostinil?
MediHelp rates the interaction as minor. Silodosin and Treprostinil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Treprostinil is a potent vasodilator and may add to the blood pressure lowering of silodosin. Patients may experience symptomatic hypotension, dizziness or syncope.
How serious is the interaction between Silodosin and Treprostinil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and orthostatic symptoms when starting or adjusting either drug.
What other medicines interact with Silodosin?
MediHelp also lists interactions of Silodosin with, for example, Atazanavir, Conivaptan, Darunavir. The full list is on the Silodosin page.
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