Drug interactions
Sotalol + Triclabendazole
Severity: Major
Sotalol and Triclabendazole: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triclabendazole has been associated with QT prolongation, and sotalol is a well-known QT-prolonging drug. Combined use may raise the risk of torsades de pointes, particularly with electrolyte disturbances, bradycardia or structural heart disease.
What this interaction means in plain words
Sotalol and Triclabendazole can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Sotalol belongs to Cardiovascular; Triclabendazole belongs to Anti Parasitic.
Why it happens
Additive prolongation of ventricular repolarization (QT interval).
What to do
Avoid the combination where possible; if unavoidable, obtain a baseline ECG and correct potassium and magnesium. Monitor the QTc during treatment.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Sotalol and Triclabendazole, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Sotalol
- Arsenic trioxide + Sotalol Contraindicated
- Artemether / lumefantrine + Sotalol Contraindicated
- Disopyramide + Sotalol Contraindicated
- Dofetilide + Sotalol Contraindicated
- Dronedarone + Sotalol Contraindicated
- Droperidol + Sotalol Contraindicated
Other interactions of Triclabendazole
Frequently asked questions
Can I take Sotalol with Triclabendazole?
MediHelp rates the interaction as major. Sotalol and Triclabendazole can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Triclabendazole has been associated with QT prolongation, and sotalol is a well-known QT-prolonging drug. Combined use may raise the risk of torsades de pointes, particularly with electrolyte disturbances, bradycardia or structural heart disease.
How serious is the interaction between Sotalol and Triclabendazole?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible; if unavoidable, obtain a baseline ECG and correct potassium and magnesium. Monitor the QTc during treatment.
What other medicines interact with Sotalol?
MediHelp also lists interactions of Sotalol with, for example, Arsenic trioxide, Artemether / lumefantrine, Disopyramide. The full list is on the Sotalol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
