Drug interactions
Teriflunomide + Trastuzumab deruxtecan
Severity: Moderate
Teriflunomide and Trastuzumab deruxtecan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents can cause myelosuppression and increase susceptibility to infection. Trastuzumab deruxtecan commonly causes neutropenia, and teriflunomide can lower white cell counts.
What this interaction means in plain words
Teriflunomide and Trastuzumab deruxtecan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Teriflunomide belongs to Central Nervous System; Trastuzumab deruxtecan belongs to Oncology.
Why it happens
Additive bone marrow suppression and immunosuppression.
What to do
Monitor complete blood counts regularly and evaluate promptly for signs of infection or fever.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Teriflunomide
Other interactions of Trastuzumab deruxtecan
Frequently asked questions
Can I take Teriflunomide with Trastuzumab deruxtecan?
MediHelp rates the interaction as moderate. Teriflunomide and Trastuzumab deruxtecan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents can cause myelosuppression and increase susceptibility to infection. Trastuzumab deruxtecan commonly causes neutropenia, and teriflunomide can lower white cell counts.
How serious is the interaction between Teriflunomide and Trastuzumab deruxtecan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts regularly and evaluate promptly for signs of infection or fever.
What other medicines interact with Teriflunomide?
MediHelp also lists interactions of Teriflunomide with, for example, Ifosfamide, Lomustine, Amiodarone. The full list is on the Teriflunomide page.
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