Drug interactions
Testosterone + Vildagliptin
Severity: Minor
Testosterone and Vildagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Testosterone can improve insulin sensitivity and glycemic control, which may add to the effect of vildagliptin. The clinical effect is generally small, and hypoglycemia is unlikely with vildagliptin alone.
What this interaction means in plain words
Testosterone and Vildagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Testosterone belongs to Endocrine; Vildagliptin belongs to Endocrine.
Why it happens
Additive glucose-lowering via improved insulin sensitivity plus DPP-4 inhibition.
What to do
Monitor blood glucose after starting or changing testosterone and adjust antidiabetic therapy if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Testosterone
- Testosterone + Warfarin Major
- Androstenedione + Testosterone Moderate
- Betamethasone + Testosterone Moderate
- Carbamazepine + Testosterone Moderate
- Corticotropin + Testosterone Moderate
- Cortisone + Testosterone Moderate
Other interactions of Vildagliptin
- Ciprofloxacin + Vildagliptin Moderate
- Deflazacort + Vildagliptin Moderate
- Dexamethasone + Vildagliptin Moderate
- Gemifloxacin + Vildagliptin Moderate
- Glimepiride + Vildagliptin Moderate
- Hydrochlorothiazide-lisinopril + Vildagliptin Moderate
Frequently asked questions
Can I take Testosterone with Vildagliptin?
MediHelp rates the interaction as minor. Testosterone and Vildagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Testosterone can improve insulin sensitivity and glycemic control, which may add to the effect of vildagliptin. The clinical effect is generally small, and hypoglycemia is unlikely with vildagliptin alone.
How serious is the interaction between Testosterone and Vildagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose after starting or changing testosterone and adjust antidiabetic therapy if needed.
What other medicines interact with Testosterone?
MediHelp also lists interactions of Testosterone with, for example, Warfarin, Androstenedione, Betamethasone. The full list is on the Testosterone page.
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