تداخل‌های دارویی
Azathioprine + Valoctocogene roxaparvovec
شدت: متوسط
Azathioprine and Valoctocogene roxaparvovec: moderate interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Valoctocogene roxaparvovec commonly causes ALT elevations, and azathioprine can independently injure the liver. Concurrent use may increase the risk or severity of liver enzyme elevations and could confound their interpretation.
معنای این تداخل به زبان ساده
Azathioprine and Valoctocogene roxaparvovec can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Azathioprine belongs to Gastrointestinal Tract; Valoctocogene roxaparvovec belongs to Miscellaneous.
چرا رخ می‌دهد
Additive hepatotoxicity from the gene therapy's hepatic transduction and immune response and azathioprine's hepatotoxic potential.
اقدام لازم
Monitor liver enzymes closely, as recommended after gene therapy, and consider alternatives to azathioprine where possible. Evaluate promptly for the need for corticosteroids if ALT rises.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Azathioprine و Valoctocogene roxaparvovec، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۷ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Azathioprine
- Adenovirus types 4 and 7 live + Azathioprine منع مصرف
- Azathioprine + Bcg vaccine live منع مصرف
- Azathioprine + Febuxostat منع مصرف
- Azathioprine + Influenza virus vaccine quadrivalent intranasal منع مصرف
- Azathioprine + Measles mumps and rubella vaccine منع مصرف
- Azathioprine + Measles mumps and rubella vaccine live منع مصرف
تداخلات دیگر Valoctocogene roxaparvovec
پرسش‌های متداول
Can I take Azathioprine with Valoctocogene roxaparvovec?
MediHelp rates the interaction as moderate. Azathioprine and Valoctocogene roxaparvovec can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Valoctocogene roxaparvovec commonly causes ALT elevations, and azathioprine can independently injure the liver. Concurrent use may increase the risk or severity of liver enzyme elevations and could confound their interpretation.
How serious is the interaction between Azathioprine and Valoctocogene roxaparvovec?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor liver enzymes closely, as recommended after gene therapy, and consider alternatives to azathioprine where possible. Evaluate promptly for the need for corticosteroids if ALT rises.
What other medicines interact with Azathioprine?
MediHelp also lists interactions of Azathioprine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Febuxostat. The full list is on the Azathioprine page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
