Interactions médicamenteuses
Dexmethylphenidate + Selegiline
Gravité: Contre-indiquée
Dexmethylphenidate and Selegiline: contraindicated interaction.
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Résumé
MAO inhibitors combined with methylphenidate-type stimulants can provoke severe hypertensive crisis. Labeling contraindicates dexmethylphenidate during MAOI therapy and for 14 days afterward.
Ce que signifie cette interaction, en termes simples
Dexmethylphenidate and Selegiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dexmethylphenidate belongs to Central Nervous System; Selegiline belongs to Central Nervous System.
Pourquoi elle survient
The stimulant releases catecholamines, and MAO inhibition prevents their degradation, so they accumulate.
Conduite à tenir
Do not combine. Allow at least 14 days after stopping the MAOI before starting dexmethylphenidate.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Selegiline
- Amitriptyline + Selegiline Contre-indiquée
- Amoxapine + Selegiline Contre-indiquée
- Atomoxetine + Selegiline Contre-indiquée
- Benzphetamine + Selegiline Contre-indiquée
- Brimonidine + Selegiline Contre-indiquée
- Buprenorphine long-acting + Selegiline Contre-indiquée
Autres interactions de Dexmethylphenidate
- Dexmethylphenidate + Isocarboxazid Contre-indiquée
- Dexmethylphenidate + Linezolid Contre-indiquée
- Dexmethylphenidate + Phenelzine Contre-indiquée
- Dexmethylphenidate + Procarbazine Contre-indiquée
- Dexmethylphenidate + Rasagiline Contre-indiquée
- Dexmethylphenidate + Safinamide Contre-indiquée
Questions fréquentes
Can I take Dexmethylphenidate with Selegiline?
MediHelp rates the interaction as contraindicated. Dexmethylphenidate and Selegiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MAO inhibitors combined with methylphenidate-type stimulants can provoke severe hypertensive crisis. Labeling contraindicates dexmethylphenidate during MAOI therapy and for 14 days afterward.
How serious is the interaction between Dexmethylphenidate and Selegiline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine. Allow at least 14 days after stopping the MAOI before starting dexmethylphenidate.
What other medicines interact with Selegiline?
MediHelp also lists interactions of Selegiline with, for example, Amitriptyline, Amoxapine, Atomoxetine. The full list is on the Selegiline page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
