Interactions médicamenteuses
Dexmethylphenidate + Rasagiline
Gravité: Contre-indiquée
Dexmethylphenidate and Rasagiline: contraindicated interaction.
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Résumé
Stimulants such as dexmethylphenidate given with MAO inhibitors may cause hypertensive crisis. Labeling contraindicates use during and for 14 days after MAO inhibitor therapy.
Ce que signifie cette interaction, en termes simples
Dexmethylphenidate and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dexmethylphenidate belongs to Central Nervous System; Rasagiline belongs to Central Nervous System.
Pourquoi elle survient
Dexmethylphenidate increases synaptic catecholamines and MAO inhibition prevents their breakdown, causing additive pressor effects.
Conduite à tenir
Avoid the combination and separate by at least 14 days after stopping the MAO inhibitor. Use a non-stimulant alternative if needed.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Rasagiline
- Atomoxetine + Rasagiline Contre-indiquée
- Brimonidine + Rasagiline Contre-indiquée
- Bupropion-naltrexone + Rasagiline Contre-indiquée
- Bupropion + Rasagiline Contre-indiquée
- Clomipramine + Rasagiline Contre-indiquée
- Desvenlafaxine + Rasagiline Contre-indiquée
Autres interactions de Dexmethylphenidate
- Dexmethylphenidate + Isocarboxazid Contre-indiquée
- Dexmethylphenidate + Linezolid Contre-indiquée
- Dexmethylphenidate + Phenelzine Contre-indiquée
- Dexmethylphenidate + Procarbazine Contre-indiquée
- Dexmethylphenidate + Safinamide Contre-indiquée
- Dexmethylphenidate + Selegiline Contre-indiquée
Questions fréquentes
Can I take Dexmethylphenidate with Rasagiline?
MediHelp rates the interaction as contraindicated. Dexmethylphenidate and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Stimulants such as dexmethylphenidate given with MAO inhibitors may cause hypertensive crisis. Labeling contraindicates use during and for 14 days after MAO inhibitor therapy.
How serious is the interaction between Dexmethylphenidate and Rasagiline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and separate by at least 14 days after stopping the MAO inhibitor. Use a non-stimulant alternative if needed.
What other medicines interact with Rasagiline?
MediHelp also lists interactions of Rasagiline with, for example, Atomoxetine, Brimonidine, Bupropion-naltrexone. The full list is on the Rasagiline page.
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