Interazioni tra farmaci
Moxifloxacin + Pentamidine
Gravità: Controindicata
Moxifloxacin and Pentamidine: contraindicated interaction.
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Sintesi
Both agents can prolong the QT interval, and pentamidine has been associated with torsades de pointes. Together they increase the chance of life-threatening ventricular arrhythmia.
Cosa significa questa interazione in parole semplici
Moxifloxacin and Pentamidine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Moxifloxacin belongs to Anti Bacterial; Pentamidine belongs to Anti Parasitic.
Perché avviene
Additive QT prolongation through effects on cardiac repolarization currents.
Cosa fare
Avoid the combination and select a non-QT-prolonging antibiotic. If pentamidine is essential, obtain baseline and follow-up ECGs and correct potassium and magnesium.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Moxifloxacin
- Amiodarone + Moxifloxacin Controindicata
- Arsenic trioxide + Moxifloxacin Controindicata
- Disopyramide + Moxifloxacin Controindicata
- Dofetilide + Moxifloxacin Controindicata
- Dronedarone + Moxifloxacin Controindicata
- Droperidol + Moxifloxacin Controindicata
Altre interazioni di Pentamidine
- Clomipramine + Pentamidine Controindicata
- Desipramine + Pentamidine Controindicata
- Dronedarone + Pentamidine Controindicata
- Nortriptyline + Pentamidine Controindicata
- Pentamidine + Pimozide Controindicata
- Pentamidine + Thioridazine Controindicata
Domande frequenti
Can I take Moxifloxacin with Pentamidine?
MediHelp rates the interaction as contraindicated. Moxifloxacin and Pentamidine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents can prolong the QT interval, and pentamidine has been associated with torsades de pointes. Together they increase the chance of life-threatening ventricular arrhythmia.
How serious is the interaction between Moxifloxacin and Pentamidine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and select a non-QT-prolonging antibiotic. If pentamidine is essential, obtain baseline and follow-up ECGs and correct potassium and magnesium.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
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