医薬品リファレンス
Cefotetan
Cefotetan is a medicine in the class anti bacterial. It is used for bone & joint infections.
- 薬効分類: Anti Bacterial
- 効能・効果: bone & joint infections
最終更新日 出典: US FDA label
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Anti Bacterial
- 一般的な剤形
- 注射剤
- 既知の相互作用
- 19 (併用禁忌: 1 · 重大: 1 · 中等度: 9 · 軽度: 8)
- 商品名
- 2
- 国・市場
- 1
何に使われるか
作用のしくみ
Bactericidal agent that acts by inhibiting bacterial cell wall synthesis; active in the presence of some beta-lactamases.
成人の通常用量（添付文書の要約）
Treatment of infections: 1 g or 2 g, intravenously or intramuscularly; dose and route determined by patient condition, severity and organism susceptibility
妊娠と授乳
- 妊娠
- Unknown No adequate and well-controlled studies in pregnant women; use only if clearly needed. Animal studies showed no harm to the fetus.
- 授乳
- Unknown Excreted in human milk in very low concentrations; exercise caution in nursing women.
報告されている副作用
- Diarrhea
- Nausea
- Eosinophilia
- Positive direct Coombs test
- Elevated ALT
- Rash
禁忌
- Known allergy to the cephalosporin group of antibiotics
- History of cephalosporin associated hemolytic anemia
注意が必要な方
- Check for previous hypersensitivity to cephalosporins, penicillins or other drugs; cross-hypersensitivity among beta-lactams may occur in up to 10% of penicillin-allergic patients. Discontinue if allergic reaction occurs.
- Immune mediated hemolytic anemia, including fatal cases, with at least 3 fold increased risk versus other cephalosporins; consider if anemia develops within 2 to 3 weeks after dosing, stop drug and monitor hematologic parameters.
- Clostridium difficile associated diarrhea may occur, even over two months after antibiotic use.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (19)
- Cefotetan + Dronabinol Contraindicated
- Cefotetan + Warfarin Major
- Amikacin + Cefotetan Moderate
- Argatroban + Cefotetan Moderate
- Cefotetan + Dalteparin Moderate
- Cefotetan + Enoxaparin Moderate
- Cefotetan + Fondaparinux Moderate
- Cefotetan + Gentamicin Moderate
- Cefotetan + Heparin Moderate
- Cefotetan + Streptomycin Moderate
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Cefotetanの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
- IV preparation and dilution
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同じ分類のほかの薬剤
よくある質問
What is Cefotetan used for?
Cefotetan is a medicine in the class anti bacterial. It is used for Bone & joint infections, Gynecologic infections, Intra-abdominal infections, Lower respiratory tract, Skin infections, Urinary tract infections.
What side effects have been reported with Cefotetan?
Diarrhea, Nausea, Eosinophilia, Positive direct Coombs test, Elevated ALT, Rash.
Can Cefotetan be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. No adequate and well-controlled studies in pregnant women; use only if clearly needed. Animal studies showed no harm to the fetus. Breastfeeding: Unknown. Excreted in human milk in very low concentrations; exercise caution in nursing women.
What does Cefotetan interact with?
MediHelp lists 19 known interactions for Cefotetan. Contraindicated: 1 · Major: 1 · Moderate: 9 · Minor: 8. The most serious include Dronabinol, Warfarin, Amikacin.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
