Interações medicamentosas
Benazepril + Isosorbide dinitrate
Gravidade: Moderada
Benazepril and Isosorbide dinitrate: moderate interaction.
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Resumo
Nitrates cause venous and arterial dilation, and combining them with an ACE inhibitor can lower blood pressure further. This is often used intentionally but may cause symptomatic hypotension, especially at initiation.
O que esta interação significa em palavras simples
Benazepril and Isosorbide dinitrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Benazepril belongs to Cardiovascular; Isosorbide dinitrate belongs to Cardiovascular.
Por que acontece
Additive vasodilatory and hypotensive effects.
O que fazer
Monitor blood pressure and orthostatic symptoms when starting or increasing either drug. Adjust doses if symptomatic hypotension occurs.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Benazepril
- Aliskiren + Benazepril Contraindicada
- Benazepril + Sacubitril / valsartan Contraindicada
- Benazepril + Sacubitril-valsartan Contraindicada
- Amifostine + Benazepril Grave
- Amiloride + Benazepril Grave
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Grave
Outras interações de Isosorbide dinitrate
- Avanafil + Isosorbide dinitrate Contraindicada
- Isosorbide dinitrate + Riociguat Contraindicada
- Isosorbide dinitrate + Sildenafil Contraindicada
- Isosorbide dinitrate + Tadalafil Contraindicada
- Isosorbide dinitrate + Vardenafil Contraindicada
- Ergotamine + Isosorbide dinitrate Grave
Perguntas frequentes
Can I take Benazepril with Isosorbide dinitrate?
MediHelp rates the interaction as moderate. Benazepril and Isosorbide dinitrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nitrates cause venous and arterial dilation, and combining them with an ACE inhibitor can lower blood pressure further. This is often used intentionally but may cause symptomatic hypotension, especially at initiation.
How serious is the interaction between Benazepril and Isosorbide dinitrate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and orthostatic symptoms when starting or increasing either drug. Adjust doses if symptomatic hypotension occurs.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
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