藥品參考
Miconazole
Miconazole is a medicine in the class anti fungals. It is used for oropharyngeal candidiasis.
- 藥物類別: Anti Fungals
- 用途: oropharyngeal candidiasis
最後更新 來源: US FDA label, UK SmPC, Base de donnees publique des medicaments (France), ANSM Base de donnees publique des medicaments (RCP, French)
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Anti Fungals
- 常見劑型
- 乳膏, 粉劑, 凝膠, 吸入器, 軟膏, 溶液
- 常見規格
- 2 g/100 g, 2%, 20 mg/g
- 已知交互作用
- 50 (嚴重: 12 · 中度: 24 · 輕微: 14)
- 商品名
- 232
- 國家與市場
- 5
用途
作用方式
Azole antifungal agent; inhibits enzyme cytochrome P450 14-alpha-demethylase resulting in ergosterol synthesis inhibition
成人常用劑量（仿單摘要）
Oropharyngeal Candidiasis: Apply 50 mg buccal tab to gum region qDay for 14 consecutive days
懷孕與哺乳
- 懷孕
- Unknown Vaginal and skin forms: little is absorbed; topical azoles are preferred for thrush in pregnancy. Oral gel and buccal tablets are more absorbed; the buccal label warns of possible fetal harm from animal data, so avoid them if possible (nystatin is an option for mouth thrush).
- 哺乳
- Safe No data for buccal tablets. Poorly absorbed from skin, vagina and gut, so unlikely to affect the infant (LactMed), including when used on the nipples; remove excess before feeds and prefer creams or gels to ointments on the breast.
已通報的副作用
- Irritation
- Diarrhea
- Nausea
- Allergic contact dermatitis
- Burning
禁忌症
- Hypersensitivity to drug, milk protein concentrate, or other excipients
哪些人需要特別留意
- Miconazole is systemically absorbed and inhibits CYP2C9 and CYP3A4, prolonging the effect of warfarin; bleeding events, some fatal, have been reported with oral gel. Monitor the anticoagulant effect carefully if coumarin anticoagulants are used concomitantly.
- Choking risk in infants and young children (4 months to 2 years): do not apply the gel to the back of the throat, divide each dose into small portions and observe the patient. Do not apply it to a nipple for infant administration.
- Severe hypersensitivity reactions including anaphylaxis and angioedema have been reported; stop treatment if hypersensitivity or irritation occurs.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (50)
- Cabazitaxel + Miconazole Major
- Dihydroergotamine + Miconazole Major
- Dihydroergotamine intranasal + Miconazole Major
- Ergotamine + Miconazole Major
- Glyburide + Miconazole Major
- Lovastatin + Miconazole Major
- Methadone + Miconazole Major
- Miconazole + Pimozide Major
- Miconazole + Ribociclib Major
- Miconazole + Simvastatin Major
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Miconazole 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
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同類別的其他藥品
常見問題
What is Miconazole used for?
Miconazole is a medicine in the class anti fungals. It is used for Oropharyngeal candidiasis, Tinea, Vulvovaginal candidiasis.
What side effects have been reported with Miconazole?
Irritation, Diarrhea, Nausea, Allergic contact dermatitis, Burning.
Can Miconazole be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Vaginal and skin forms: little is absorbed; topical azoles are preferred for thrush in pregnancy. Oral gel and buccal tablets are more absorbed; the buccal label warns of possible fetal harm from animal data, so avoid them if possible (nystatin is an option for mouth thrush). Breastfeeding: Safe. No data for buccal tablets. Poorly absorbed from skin, vagina and gut, so unlikely to affect the infant (LactMed), including when used on the nipples; remove excess before feeds and prefer creams or gels to ointments on the breast.
What does Miconazole interact with?
MediHelp lists 50 known interactions for Miconazole. Major: 12 · Moderate: 24 · Minor: 14. The most serious include Cabazitaxel, Dihydroergotamine, Dihydroergotamine intranasal.
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