藥品參考
Tofacitinib
Tofacitinib is a medicine in the class musculoskeletal. It is used for ankylosing spondylitis.
- 藥物類別: Musculoskeletal
- 用途: ankylosing spondylitis
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Musculoskeletal
- ATC 代碼
- L04AF01
- 常見劑型
- 錠劑, 溶液
- 常見規格
- 5 mg, 11 mg, 10 mg
- 已知交互作用
- 200 (禁忌併用: 3 · 嚴重: 111 · 中度: 55 · 輕微: 31)
- 商品名
- 9
- 國家與市場
- 5
用途
作用方式
Janus kinases (JAKs) pathways inhibitor; JAK consists of a group of intracellular tyrosine kinases that transmit signals from cytokine or growth factor-receptor interactions on the cellular membrane to influence cellular processes of hematopoieses and immune cell function
成人常用劑量（仿單摘要）
Rheumatoid Arthritis & Psoriatic Arthritis & Ankylosing Spondylitis (Xeljanz): 5 mg PO BID OR (Xeljanz XR): 11 mg PO qDay
懷孕與哺乳
- 懷孕
- Unsafe According to some authorities: As a precaution, use is contraindicated.
- 哺乳
- Unsafe According to some authorities: As a precaution, use is contraindicated.
已通報的副作用
- Headache
- Upper respiratory tract infection
- Nasopharyngitis
- Diarrhea
- Elevated cholesterol levels
哪些人需要特別留意
- ncreased risk for developing serious infections that may lead to hospitalization or death
- Malignancies, including lymphoma and solid tumors, reported
- GI perforation reported, although role of JAK inhibition in these events is unknown
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (200)
- Baricitinib + Tofacitinib Contraindicated
- Cladribine + Tofacitinib Contraindicated
- Tofacitinib + Upadacitinib Contraindicated
- Abatacept + Tofacitinib Major
- Anti-thymocyte + Tofacitinib Major
- Antithymocyte globulin equine + Tofacitinib Major
- Antithymocyte globulin rabbit + Tofacitinib Major
- Apalutamide + Tofacitinib Major
- Atazanavir + Tofacitinib Major
- Axicabtagene ciloleucel + Tofacitinib Major
同類別的其他藥品
相關快速閱讀
常見問題
What is Tofacitinib used for?
Tofacitinib is a medicine in the class musculoskeletal. It is used for Ankylosing spondylitis, Juvenile rheumatoid arthritis, Psoriatic arthritis, Rheumatoid arthritis, Ulcerative colitis.
What side effects have been reported with Tofacitinib?
Headache, Upper respiratory tract infection, Nasopharyngitis, Diarrhea, Elevated cholesterol levels.
Can Tofacitinib be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. According to some authorities: As a precaution, use is contraindicated. Breastfeeding: Unsafe. According to some authorities: As a precaution, use is contraindicated.
What does Tofacitinib interact with?
MediHelp lists 200 known interactions for Tofacitinib. Contraindicated: 3 · Major: 111 · Moderate: 55 · Minor: 31. The most serious include Baricitinib, Cladribine, Upadacitinib.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
