藥物交互作用
Amlodipine-olmesartan-hydrochlorothiazide + Calcium gluconate
嚴重程度: 中度
Amlodipine-olmesartan-hydrochlorothiazide and Calcium gluconate: moderate interaction.
最後更新
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摘要
Intravenous calcium gluconate can reduce the effect of amlodipine and is used in calcium channel blocker overdose. With thiazides, calcium load can also cause hypercalcemia.
用白話說明這項交互作用的意義
Amlodipine-olmesartan-hydrochlorothiazide and Calcium gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Calcium gluconate belongs to Gastrointestinal Tract.
為什麼會發生
Increased extracellular calcium counteracts L-type calcium channel blockade; thiazide decreases urinary calcium excretion.
處置方式
Monitor blood pressure and serum calcium during parenteral calcium therapy and anticipate reduced amlodipine effect.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amlodipine-olmesartan-hydrochlorothiazide 的其他交互作用
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide 禁忌併用
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide 禁忌併用
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan 禁忌併用
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide 嚴重
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide 嚴重
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide 嚴重
Calcium gluconate 的其他交互作用
常見問題
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Calcium gluconate?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan-hydrochlorothiazide and Calcium gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Intravenous calcium gluconate can reduce the effect of amlodipine and is used in calcium channel blocker overdose. With thiazides, calcium load can also cause hypercalcemia.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Calcium gluconate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and serum calcium during parenteral calcium therapy and anticipate reduced amlodipine effect.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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