藥物交互作用
Amlodipine-hydrochlorothiazide-valsartan + Calcium gluconate
嚴重程度: 中度
Amlodipine-hydrochlorothiazide-valsartan and Calcium gluconate: moderate interaction.
最後更新
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摘要
Intravenous calcium gluconate can counteract the effects of amlodipine and is used in calcium channel blocker toxicity. Thiazide diuretics also reduce calcium excretion, which may raise serum calcium.
用白話說明這項交互作用的意義
Amlodipine-hydrochlorothiazide-valsartan and Calcium gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-hydrochlorothiazide-valsartan belongs to Cardiovascular; Calcium gluconate belongs to Gastrointestinal Tract.
為什麼會發生
Raised extracellular calcium opposes L-type calcium channel blockade; thiazides decrease urinary calcium loss.
處置方式
Monitor blood pressure and serum calcium during parenteral calcium administration. Adjust antihypertensive therapy if blood pressure control is lost.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amlodipine-hydrochlorothiazide-valsartan 的其他交互作用
- Aliskiren + Amlodipine-hydrochlorothiazide-valsartan 禁忌併用
- Amlodipine-hydrochlorothiazide-valsartan + Dofetilide 禁忌併用
- Amlodipine-hydrochlorothiazide-valsartan + Sparsentan 禁忌併用
- Aceclofenac + Amlodipine-hydrochlorothiazide-valsartan 嚴重
- Aldesleukin + Amlodipine-hydrochlorothiazide-valsartan 嚴重
- Amifostine + Amlodipine-hydrochlorothiazide-valsartan 嚴重
Calcium gluconate 的其他交互作用
常見問題
Can I take Amlodipine-hydrochlorothiazide-valsartan with Calcium gluconate?
MediHelp rates the interaction as moderate. Amlodipine-hydrochlorothiazide-valsartan and Calcium gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Intravenous calcium gluconate can counteract the effects of amlodipine and is used in calcium channel blocker toxicity. Thiazide diuretics also reduce calcium excretion, which may raise serum calcium.
How serious is the interaction between Amlodipine-hydrochlorothiazide-valsartan and Calcium gluconate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and serum calcium during parenteral calcium administration. Adjust antihypertensive therapy if blood pressure control is lost.
What other medicines interact with Amlodipine-hydrochlorothiazide-valsartan?
MediHelp also lists interactions of Amlodipine-hydrochlorothiazide-valsartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-hydrochlorothiazide-valsartan page.
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