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藥物交互作用

Calcium gluconate + Digoxin

嚴重程度: 嚴重

Calcium gluconate and Digoxin: major interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Intravenous calcium gluconate in a digitalized patient may precipitate arrhythmias through additive effects on myocardial calcium handling, though it is less concentrated than calcium chloride.

用白話說明這項交互作用的意義

Calcium gluconate and Digoxin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Calcium gluconate belongs to Gastrointestinal Tract; Digoxin belongs to Cardiovascular.

證據等級: Moderate

為什麼會發生

Acute hypercalcemia augments digoxin-induced intracellular calcium loading and ventricular automaticity.

處置方式

Avoid IV calcium in patients on digoxin unless necessary; if given, infuse slowly with continuous ECG monitoring.

可向藥師詢問的問題

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Calcium gluconate with Digoxin?

MediHelp rates the interaction as major. Calcium gluconate and Digoxin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Intravenous calcium gluconate in a digitalized patient may precipitate arrhythmias through additive effects on myocardial calcium handling, though it is less concentrated than calcium chloride.

How serious is the interaction between Calcium gluconate and Digoxin?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid IV calcium in patients on digoxin unless necessary; if given, infuse slowly with continuous ECG monitoring.

What other medicines interact with Digoxin?

MediHelp also lists interactions of Digoxin with, for example, Lily of the valley, Squill, Adagrasib. The full list is on the Digoxin page.

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