藥物交互作用
Calcium gluconate + Digoxin
嚴重程度: 嚴重
Calcium gluconate and Digoxin: major interaction.
最後更新
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摘要
Intravenous calcium gluconate in a digitalized patient may precipitate arrhythmias through additive effects on myocardial calcium handling, though it is less concentrated than calcium chloride.
用白話說明這項交互作用的意義
Calcium gluconate and Digoxin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Calcium gluconate belongs to Gastrointestinal Tract; Digoxin belongs to Cardiovascular.
為什麼會發生
Acute hypercalcemia augments digoxin-induced intracellular calcium loading and ventricular automaticity.
處置方式
Avoid IV calcium in patients on digoxin unless necessary; if given, infuse slowly with continuous ECG monitoring.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Digoxin 的其他交互作用
Calcium gluconate 的其他交互作用
常見問題
Can I take Calcium gluconate with Digoxin?
MediHelp rates the interaction as major. Calcium gluconate and Digoxin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Intravenous calcium gluconate in a digitalized patient may precipitate arrhythmias through additive effects on myocardial calcium handling, though it is less concentrated than calcium chloride.
How serious is the interaction between Calcium gluconate and Digoxin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid IV calcium in patients on digoxin unless necessary; if given, infuse slowly with continuous ECG monitoring.
What other medicines interact with Digoxin?
MediHelp also lists interactions of Digoxin with, for example, Lily of the valley, Squill, Adagrasib. The full list is on the Digoxin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。