藥物交互作用
Calcium gluconate + Ceftriaxone
嚴重程度: 禁忌併用
Calcium gluconate and Ceftriaxone: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Ceftriaxone can form insoluble ceftriaxone-calcium salts when it meets calcium-containing solutions. Fatal cases have occurred in neonates with crystalline deposits in the lungs and kidneys. Precipitation can also occur in the infusion line or in the body after separate infusions.
用白話說明這項交互作用的意義
Calcium gluconate and Ceftriaxone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Calcium gluconate belongs to Gastrointestinal Tract; Ceftriaxone belongs to Anti Bacterial.
為什麼會發生
Ceftriaxone binds calcium to form poorly soluble ceftriaxone-calcium precipitate.
處置方式
Never mix or co-infuse ceftriaxone with calcium-containing IV solutions, and in neonates avoid concurrent use entirely. In patients older than 28 days, give sequentially only with thorough line flushing between infusions using a compatible fluid.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Ceftriaxone 的其他交互作用
Calcium gluconate 的其他交互作用
常見問題
Can I take Calcium gluconate with Ceftriaxone?
MediHelp rates the interaction as contraindicated. Calcium gluconate and Ceftriaxone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ceftriaxone can form insoluble ceftriaxone-calcium salts when it meets calcium-containing solutions. Fatal cases have occurred in neonates with crystalline deposits in the lungs and kidneys. Precipitation can also occur in the infusion line or in the body after separate infusions.
How serious is the interaction between Calcium gluconate and Ceftriaxone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Never mix or co-infuse ceftriaxone with calcium-containing IV solutions, and in neonates avoid concurrent use entirely. In patients older than 28 days, give sequentially only with thorough line flushing between infusions using a compatible fluid.
What other medicines interact with Ceftriaxone?
MediHelp also lists interactions of Ceftriaxone with, for example, Calcium chloride, Calcium, Lactated ringer's. The full list is on the Ceftriaxone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
