藥物交互作用
Amlodipine-atorvastatin + Calcium gluconate
嚴重程度: 中度
Amlodipine-atorvastatin and Calcium gluconate: moderate interaction.
最後更新
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摘要
Intravenous calcium gluconate can reverse the effects of calcium channel blockers, so a bolus may temporarily reduce the blood pressure lowering effect of amlodipine. Oral supplementation has little effect.
用白話說明這項交互作用的意義
Amlodipine-atorvastatin and Calcium gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-atorvastatin belongs to Cardiovascular; Calcium gluconate belongs to Gastrointestinal Tract.
為什麼會發生
Raised extracellular calcium competitively overcomes calcium channel blockade by amlodipine.
處置方式
Monitor blood pressure when giving intravenous calcium to patients on amlodipine; no change is needed for ordinary oral supplements.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amlodipine-atorvastatin 的其他交互作用
Calcium gluconate 的其他交互作用
常見問題
Can I take Amlodipine-atorvastatin with Calcium gluconate?
MediHelp rates the interaction as moderate. Amlodipine-atorvastatin and Calcium gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Intravenous calcium gluconate can reverse the effects of calcium channel blockers, so a bolus may temporarily reduce the blood pressure lowering effect of amlodipine. Oral supplementation has little effect.
How serious is the interaction between Amlodipine-atorvastatin and Calcium gluconate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when giving intravenous calcium to patients on amlodipine; no change is needed for ordinary oral supplements.
What other medicines interact with Amlodipine-atorvastatin?
MediHelp also lists interactions of Amlodipine-atorvastatin with, for example, Amifostine, Apalutamide, Atazanavir. The full list is on the Amlodipine-atorvastatin page.
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