藥物交互作用
Amiodarone + Fluticasone-vilanterol
嚴重程度: 嚴重
Amiodarone and Fluticasone-vilanterol: major interaction.
最後更新
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摘要
Amiodarone markedly prolongs the QT interval, and vilanterol may add tachycardia and hypokalemia. This raises the risk of torsades de pointes and other ventricular arrhythmias.
用白話說明這項交互作用的意義
Amiodarone and Fluticasone-vilanterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amiodarone belongs to Cardiovascular; Fluticasone-vilanterol belongs to Respiratory.
為什麼會發生
Additive QT prolongation with beta-2 agonist sympathetic stimulation and hypokalemia.
處置方式
Monitor ECG, potassium and magnesium, and correct deficits. Use the combination only if needed and review it if QTc increases or arrhythmia symptoms develop.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Fluticasone-vilanterol 的其他交互作用
Amiodarone 的其他交互作用
常見問題
Can I take Amiodarone with Fluticasone-vilanterol?
MediHelp rates the interaction as major. Amiodarone and Fluticasone-vilanterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Amiodarone markedly prolongs the QT interval, and vilanterol may add tachycardia and hypokalemia. This raises the risk of torsades de pointes and other ventricular arrhythmias.
How serious is the interaction between Amiodarone and Fluticasone-vilanterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG, potassium and magnesium, and correct deficits. Use the combination only if needed and review it if QTc increases or arrhythmia symptoms develop.
What other medicines interact with Fluticasone-vilanterol?
MediHelp also lists interactions of Fluticasone-vilanterol with, for example, Adagrasib, Amisulpride, Amitriptyline. The full list is on the Fluticasone-vilanterol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
