藥物交互作用
Arsenic trioxide + Fluticasone-vilanterol
嚴重程度: 嚴重
Arsenic trioxide and Fluticasone-vilanterol: major interaction.
最後更新
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摘要
Arsenic trioxide markedly prolongs the QT interval and can cause torsade de pointes. Vilanterol may add to this through beta-agonist effects on heart rate and potassium, raising arrhythmia risk in an already vulnerable patient.
用白話說明這項交互作用的意義
Arsenic trioxide and Fluticasone-vilanterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Arsenic trioxide belongs to Oncology; Fluticasone-vilanterol belongs to Respiratory.
為什麼會發生
Additive QT prolongation with beta2-agonist-related hypokalemia and sympathetic stimulation.
處置方式
Prefer a non-beta-agonist alternative where possible. If used, monitor ECG and keep potassium and magnesium within normal range throughout arsenic therapy.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Fluticasone-vilanterol 的其他交互作用
Arsenic trioxide 的其他交互作用
常見問題
Can I take Arsenic trioxide with Fluticasone-vilanterol?
MediHelp rates the interaction as major. Arsenic trioxide and Fluticasone-vilanterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Arsenic trioxide markedly prolongs the QT interval and can cause torsade de pointes. Vilanterol may add to this through beta-agonist effects on heart rate and potassium, raising arrhythmia risk in an already vulnerable patient.
How serious is the interaction between Arsenic trioxide and Fluticasone-vilanterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prefer a non-beta-agonist alternative where possible. If used, monitor ECG and keep potassium and magnesium within normal range throughout arsenic therapy.
What other medicines interact with Fluticasone-vilanterol?
MediHelp also lists interactions of Fluticasone-vilanterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Fluticasone-vilanterol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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