藥物交互作用
Aripiprazole + Guanfacine
嚴重程度: 中度
Aripiprazole and Guanfacine: moderate interaction.
最後更新
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摘要
Both drugs can lower blood pressure, so the combination can cause dizziness, orthostatic hypotension and syncope. Additive sedation is also possible.
用白話說明這項交互作用的意義
Aripiprazole and Guanfacine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aripiprazole belongs to Central Nervous System; Guanfacine belongs to Cardiovascular.
為什麼會發生
Additive hypotensive and sedative effects from central alpha-2 agonism and alpha-1 blockade.
處置方式
Monitor blood pressure and heart rate, including standing readings, especially at start or dose changes. Advise rising slowly and adjust doses if symptomatic.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Aripiprazole 的其他交互作用
Guanfacine 的其他交互作用
常見問題
Can I take Aripiprazole with Guanfacine?
MediHelp rates the interaction as moderate. Aripiprazole and Guanfacine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can lower blood pressure, so the combination can cause dizziness, orthostatic hypotension and syncope. Additive sedation is also possible.
How serious is the interaction between Aripiprazole and Guanfacine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate, including standing readings, especially at start or dose changes. Advise rising slowly and adjust doses if symptomatic.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
