藥物交互作用
Amisulpride + Guanfacine
嚴重程度: 中度
Amisulpride and Guanfacine: moderate interaction.
最後更新
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摘要
Guanfacine causes somnolence, and amisulpride can add to the sedative effect. Both may also lower blood pressure or heart rate, which may add to dizziness.
用白話說明這項交互作用的意義
Amisulpride and Guanfacine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amisulpride belongs to Central Nervous System; Guanfacine belongs to Cardiovascular.
為什麼會發生
Additive CNS depression and hypotension from alpha-2 agonism and dopamine D2/alpha-adrenergic effects.
處置方式
Monitor sedation, blood pressure and heart rate, particularly after dose changes. Titrate guanfacine slowly.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amisulpride 的其他交互作用
Guanfacine 的其他交互作用
常見問題
Can I take Amisulpride with Guanfacine?
MediHelp rates the interaction as moderate. Amisulpride and Guanfacine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Guanfacine causes somnolence, and amisulpride can add to the sedative effect. Both may also lower blood pressure or heart rate, which may add to dizziness.
How serious is the interaction between Amisulpride and Guanfacine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor sedation, blood pressure and heart rate, particularly after dose changes. Titrate guanfacine slowly.
What other medicines interact with Amisulpride?
MediHelp also lists interactions of Amisulpride with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Amisulpride page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。