藥物交互作用
Atorvastatin + Darolutamide
嚴重程度: 中度
Atorvastatin and Darolutamide: moderate interaction.
最後更新
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摘要
Darolutamide inhibits BCRP, which can increase exposure to atorvastatin. Higher statin levels may raise the risk of muscle toxicity.
用白話說明這項交互作用的意義
Atorvastatin and Darolutamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atorvastatin belongs to Cardiovascular; Darolutamide belongs to Miscellaneous.
為什麼會發生
Darolutamide inhibits BCRP (and OATP1B) transport, raising atorvastatin concentrations.
處置方式
Monitor for myopathy and consider reducing the atorvastatin dose during darolutamide therapy.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Atorvastatin 的其他交互作用
Darolutamide 的其他交互作用
常見問題
Can I take Atorvastatin with Darolutamide?
MediHelp rates the interaction as moderate. Atorvastatin and Darolutamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Darolutamide inhibits BCRP, which can increase exposure to atorvastatin. Higher statin levels may raise the risk of muscle toxicity.
How serious is the interaction between Atorvastatin and Darolutamide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for myopathy and consider reducing the atorvastatin dose during darolutamide therapy.
What other medicines interact with Atorvastatin?
MediHelp also lists interactions of Atorvastatin with, for example, Tipranavir, Atazanavir, Clarithromycin. The full list is on the Atorvastatin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
