藥物交互作用
Avatrombopag + Enzalutamide
嚴重程度: 中度
Avatrombopag and Enzalutamide: moderate interaction.
最後更新
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摘要
Enzalutamide induces CYP3A4 and CYP2C9 and can lower avatrombopag exposure, reducing platelet response. This may lead to inadequate platelet counts.
用白話說明這項交互作用的意義
Avatrombopag and Enzalutamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Avatrombopag belongs to Miscellaneous; Enzalutamide belongs to Endocrine.
為什麼會發生
Induction of CYP3A4 and CYP2C9 by enzalutamide increases avatrombopag clearance.
處置方式
Monitor platelet counts and increase avatrombopag dose per labeling for dual inducers; reassess when enzalutamide is stopped.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Enzalutamide 的其他交互作用
Avatrombopag 的其他交互作用
常見問題
Can I take Avatrombopag with Enzalutamide?
MediHelp rates the interaction as moderate. Avatrombopag and Enzalutamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Enzalutamide induces CYP3A4 and CYP2C9 and can lower avatrombopag exposure, reducing platelet response. This may lead to inadequate platelet counts.
How serious is the interaction between Avatrombopag and Enzalutamide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor platelet counts and increase avatrombopag dose per labeling for dual inducers; reassess when enzalutamide is stopped.
What other medicines interact with Enzalutamide?
MediHelp also lists interactions of Enzalutamide with, for example, Doravirine, Elbasvir / grazoprevir, Ensitrelvir. The full list is on the Enzalutamide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
