藥物交互作用
Avatrombopag + Carbamazepine
嚴重程度: 中度
Avatrombopag and Carbamazepine: moderate interaction.
最後更新
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摘要
Carbamazepine can reduce avatrombopag exposure and may cause inadequate platelet response. Labeling advises adjusting the starting dose in ITP when combined with such inducers.
用白話說明這項交互作用的意義
Avatrombopag and Carbamazepine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Avatrombopag belongs to Miscellaneous; Carbamazepine belongs to Central Nervous System.
為什麼會發生
Carbamazepine induces CYP3A4 and CYP2C9, increasing avatrombopag metabolism.
處置方式
Follow labeled dose adjustment for dual inducers and monitor platelet counts, adjusting the dose to response.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Carbamazepine 的其他交互作用
Avatrombopag 的其他交互作用
常見問題
Can I take Avatrombopag with Carbamazepine?
MediHelp rates the interaction as moderate. Avatrombopag and Carbamazepine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Carbamazepine can reduce avatrombopag exposure and may cause inadequate platelet response. Labeling advises adjusting the starting dose in ITP when combined with such inducers.
How serious is the interaction between Avatrombopag and Carbamazepine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Follow labeled dose adjustment for dual inducers and monitor platelet counts, adjusting the dose to response.
What other medicines interact with Carbamazepine?
MediHelp also lists interactions of Carbamazepine with, for example, Artemether / lumefantrine, Cabotegravir, Delamanid. The full list is on the Carbamazepine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
