藥物交互作用
Baloxavir marboxil + Magnesium sulphate
嚴重程度: 中度
Baloxavir marboxil and Magnesium sulphate: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Polyvalent cations such as magnesium can chelate baloxavir in the gut and reduce its absorption, which could lower antiviral exposure and weaken influenza treatment or prophylaxis. This is mainly relevant to oral magnesium products, not parenteral magnesium sulfate.
用白話說明這項交互作用的意義
Baloxavir marboxil and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Baloxavir marboxil belongs to Anti Virals; Magnesium sulphate belongs to Cardiovascular.
為什麼會發生
Chelation of baloxavir by magnesium in the gastrointestinal tract reduces its oral absorption.
處置方式
Avoid taking baloxavir together with oral magnesium-containing laxatives, antacids or supplements; if needed, give baloxavir at a different time and consider the product labeling advice on separation. Parenteral magnesium does not need separation.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Magnesium sulphate 的其他交互作用
Baloxavir marboxil 的其他交互作用
常見問題
Can I take Baloxavir marboxil with Magnesium sulphate?
MediHelp rates the interaction as moderate. Baloxavir marboxil and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Polyvalent cations such as magnesium can chelate baloxavir in the gut and reduce its absorption, which could lower antiviral exposure and weaken influenza treatment or prophylaxis. This is mainly relevant to oral magnesium products, not parenteral magnesium sulfate.
How serious is the interaction between Baloxavir marboxil and Magnesium sulphate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid taking baloxavir together with oral magnesium-containing laxatives, antacids or supplements; if needed, give baloxavir at a different time and consider the product labeling advice on separation. Parenteral magnesium does not need separation.
What other medicines interact with Magnesium sulphate?
MediHelp also lists interactions of Magnesium sulphate with, for example, Amikacin, Amphotericin b deoxycholate, Atracurium. The full list is on the Magnesium sulphate page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
