藥物交互作用
Ciprofloxacin + Magnesium sulphate
嚴重程度: 中度
Ciprofloxacin and Magnesium sulphate: moderate interaction.
最後更新
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摘要
Oral magnesium-containing products bind ciprofloxacin in the gut and markedly reduce its absorption, potentially causing treatment failure. Intravenous magnesium does not cause this interaction.
用白話說明這項交互作用的意義
Ciprofloxacin and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ciprofloxacin belongs to Anti Bacterial; Magnesium sulphate belongs to Cardiovascular.
為什麼會發生
Chelation of ciprofloxacin by divalent magnesium cations in the gastrointestinal tract forms poorly absorbed complexes.
處置方式
Give oral ciprofloxacin at least 2 hours before or 6 hours after oral magnesium. Use an alternative if separation is not feasible.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Magnesium sulphate 的其他交互作用
Ciprofloxacin 的其他交互作用
常見問題
Can I take Ciprofloxacin with Magnesium sulphate?
MediHelp rates the interaction as moderate. Ciprofloxacin and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral magnesium-containing products bind ciprofloxacin in the gut and markedly reduce its absorption, potentially causing treatment failure. Intravenous magnesium does not cause this interaction.
How serious is the interaction between Ciprofloxacin and Magnesium sulphate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral ciprofloxacin at least 2 hours before or 6 hours after oral magnesium. Use an alternative if separation is not feasible.
What other medicines interact with Magnesium sulphate?
MediHelp also lists interactions of Magnesium sulphate with, for example, Amikacin, Amphotericin b deoxycholate, Atracurium. The full list is on the Magnesium sulphate page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
