藥物交互作用
Cisatracurium + Magnesium sulphate
嚴重程度: 中度
Cisatracurium and Magnesium sulphate: moderate interaction.
最後更新
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摘要
Parenteral magnesium sulfate enhances the effect of cisatracurium, leading to a deeper and longer neuromuscular block. Delayed recovery may prolong ventilatory support.
用白話說明這項交互作用的意義
Cisatracurium and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cisatracurium belongs to Musculoskeletal; Magnesium sulphate belongs to Cardiovascular.
為什麼會發生
Magnesium decreases presynaptic acetylcholine release and reduces postjunctional sensitivity, adding to competitive neuromuscular blockade.
處置方式
Use reduced cisatracurium doses and monitor neuromuscular function with train-of-four. Anticipate prolonged recovery.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Magnesium sulphate 的其他交互作用
Cisatracurium 的其他交互作用
常見問題
Can I take Cisatracurium with Magnesium sulphate?
MediHelp rates the interaction as moderate. Cisatracurium and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Parenteral magnesium sulfate enhances the effect of cisatracurium, leading to a deeper and longer neuromuscular block. Delayed recovery may prolong ventilatory support.
How serious is the interaction between Cisatracurium and Magnesium sulphate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use reduced cisatracurium doses and monitor neuromuscular function with train-of-four. Anticipate prolonged recovery.
What other medicines interact with Magnesium sulphate?
MediHelp also lists interactions of Magnesium sulphate with, for example, Amikacin, Amphotericin b deoxycholate, Atracurium. The full list is on the Magnesium sulphate page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
