藥品參考
Magnesium sulphate
Magnesium sulphate is a medicine in the class cardiovascular. It is used for acute nephritis.
- 藥物類別: Cardiovascular
- 用途: acute nephritis
最後更新
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本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Cardiovascular
- 常見劑型
- 注射劑, 溶液
- 常見規格
- 10%, 50%, 1 g/g
- 已知交互作用
- 51 (中度: 32 · 輕微: 19)
- 商品名
- 17
- 國家與市場
- 3
用途
作用方式
Depresses CNS, blocks peripheral neuromuscular transmission, produces anticonvulsant effects; decreases amount of acetylcholine released at end-plate by motor nerve impulse Slows rate of SA node impulse formation in myocardium and prolongs conduction time
成人常用劑量（仿單摘要）
Preterm Labor (Off-label) Loading dose: 4-6 g IV over 20 minutes; maintenance: 2-4 g/hr IV for 12-24 hours as tolerated after contractions cease
懷孕與哺乳
- 懷孕
- Safe IV: treatment of choice for eclampsia and severe pre-eclampsia, also used for fetal brain protection before very preterm birth. Infusion beyond 5-7 days has caused low calcium and bone changes in the fetus; infusion before delivery can weaken newborn breathing and tone. Oral laxative: acceptable.
- 哺乳
- Safe Magnesium is a normal milk component; IV magnesium raises milk levels only slightly and the infant absorbs little. Compatible with breastfeeding (LactMed, e-lactancia). Postpartum infusion for 24 hours may delay the start of milk production.
已通報的副作用
- Circulatory collapse
- Pulmonary edema
- Respiratory paralysis
- Hypothermia
- Depressed reflexes
禁忌症
- Hypersensitivity
- Myocardial damage, diabetic coma, heart block
- Hypermagnesemia
哪些人需要特別留意
- In patients with renal impairment, ensure that renal excretory capacity is not exceeded
- Use with extreme caution in patients with myasthenia gravis or other neuromuscular disease
- Hypomagnesemia is usually associated with hypokalemia (potassium levels must be normalized)
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (51)
- Amikacin + Magnesium sulphate Moderate
- Amphotericin b deoxycholate + Magnesium sulphate Moderate
- Atracurium + Magnesium sulphate Moderate
- Baloxavir marboxil + Magnesium sulphate Moderate
- Ciprofloxacin + Magnesium sulphate Moderate
- Cisatracurium + Magnesium sulphate Moderate
- Delafloxacin + Magnesium sulphate Moderate
- Demeclocycline + Magnesium sulphate Moderate
- Doxycycline + Magnesium sulphate Moderate
- Eltrombopag + Magnesium sulphate Moderate
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Magnesium sulphate 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
- IV preparation and dilution
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同類別的其他藥品
常見問題
What is Magnesium sulphate used for?
Magnesium sulphate is a medicine in the class cardiovascular. It is used for Acute nephritis, Asthma, Hypomagnesemia, Preeclampsia, Torsades de pointes.
What side effects have been reported with Magnesium sulphate?
Circulatory collapse, Pulmonary edema, Respiratory paralysis, Hypothermia, Depressed reflexes.
Can Magnesium sulphate be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. IV: treatment of choice for eclampsia and severe pre-eclampsia, also used for fetal brain protection before very preterm birth. Infusion beyond 5-7 days has caused low calcium and bone changes in the fetus; infusion before delivery can weaken newborn breathing and tone. Oral laxative: acceptable. Breastfeeding: Safe. Magnesium is a normal milk component; IV magnesium raises milk levels only slightly and the infant absorbs little. Compatible with breastfeeding (LactMed, e-lactancia). Postpartum infusion for 24 hours may delay the start of milk production.
What does Magnesium sulphate interact with?
MediHelp lists 51 known interactions for Magnesium sulphate. Moderate: 32 · Minor: 19. The most serious include Amikacin, Amphotericin b deoxycholate, Atracurium.
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