藥物交互作用
Delafloxacin + Magnesium sulphate
嚴重程度: 中度
Delafloxacin and Magnesium sulphate: moderate interaction.
最後更新
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摘要
Oral magnesium salts can bind delafloxacin in the gut, forming chelates that are poorly absorbed. This can lower delafloxacin concentrations and risk treatment failure. The concern applies to oral magnesium products, not intravenous magnesium.
用白話說明這項交互作用的意義
Delafloxacin and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Delafloxacin belongs to Anti Bacterial; Magnesium sulphate belongs to Cardiovascular.
為什麼會發生
Chelation of delafloxacin by divalent magnesium cations in the gastrointestinal tract reduces its absorption.
處置方式
Give oral delafloxacin at least 2 hours before or 6 hours after oral magnesium-containing products.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Magnesium sulphate 的其他交互作用
Delafloxacin 的其他交互作用
常見問題
Can I take Delafloxacin with Magnesium sulphate?
MediHelp rates the interaction as moderate. Delafloxacin and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral magnesium salts can bind delafloxacin in the gut, forming chelates that are poorly absorbed. This can lower delafloxacin concentrations and risk treatment failure. The concern applies to oral magnesium products, not intravenous magnesium.
How serious is the interaction between Delafloxacin and Magnesium sulphate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral delafloxacin at least 2 hours before or 6 hours after oral magnesium-containing products.
What other medicines interact with Magnesium sulphate?
MediHelp also lists interactions of Magnesium sulphate with, for example, Amikacin, Amphotericin b deoxycholate, Atracurium. The full list is on the Magnesium sulphate page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
