藥物交互作用
Benzathine penicillin g + Leniolisib
嚴重程度: 輕微
Benzathine penicillin g and Leniolisib: minor interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Leniolisib inhibits OATP1B1 and OATP1B3, which could in theory increase levels of substrates. Penicillin G is not a clinically important OATP substrate and has a wide safety margin, so a meaningful effect is unlikely.
用白話說明這項交互作用的意義
Benzathine penicillin g and Leniolisib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Benzathine penicillin g belongs to Anti Bacterial; Leniolisib belongs to Miscellaneous.
為什麼會發生
Theoretical inhibition of hepatic OATP1B1/1B3 uptake by leniolisib.
處置方式
No dose change is needed. Monitor for penicillin adverse effects only if other risk factors exist.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Benzathine penicillin g 的其他交互作用
Leniolisib 的其他交互作用
常見問題
Can I take Benzathine penicillin g with Leniolisib?
MediHelp rates the interaction as minor. Benzathine penicillin g and Leniolisib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Leniolisib inhibits OATP1B1 and OATP1B3, which could in theory increase levels of substrates. Penicillin G is not a clinically important OATP substrate and has a wide safety margin, so a meaningful effect is unlikely.
How serious is the interaction between Benzathine penicillin g and Leniolisib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed. Monitor for penicillin adverse effects only if other risk factors exist.
What other medicines interact with Benzathine penicillin g?
MediHelp also lists interactions of Benzathine penicillin g with, for example, Cholera vaccine, Microbiota, Omadacycline. The full list is on the Benzathine penicillin g page.
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