藥物交互作用
Bleomycin + Trastuzumab deruxtecan
嚴重程度: 嚴重
Bleomycin and Trastuzumab deruxtecan: major interaction.
最後更新
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摘要
Trastuzumab deruxtecan causes neutropenia and interstitial lung disease, and bleomycin carries a risk of pulmonary toxicity and some myelosuppression. Combining them may increase infection risk and lung injury.
用白話說明這項交互作用的意義
Bleomycin and Trastuzumab deruxtecan can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bleomycin belongs to Oncology; Trastuzumab deruxtecan belongs to Oncology.
為什麼會發生
Additive myelosuppression and overlapping pulmonary toxicity.
處置方式
Monitor blood counts and respiratory symptoms closely, and evaluate promptly any new cough or dyspnea. Avoid the combination where alternatives exist.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Bleomycin 的其他交互作用
Trastuzumab deruxtecan 的其他交互作用
常見問題
Can I take Bleomycin with Trastuzumab deruxtecan?
MediHelp rates the interaction as major. Bleomycin and Trastuzumab deruxtecan can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Trastuzumab deruxtecan causes neutropenia and interstitial lung disease, and bleomycin carries a risk of pulmonary toxicity and some myelosuppression. Combining them may increase infection risk and lung injury.
How serious is the interaction between Bleomycin and Trastuzumab deruxtecan?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood counts and respiratory symptoms closely, and evaluate promptly any new cough or dyspnea. Avoid the combination where alternatives exist.
What other medicines interact with Bleomycin?
MediHelp also lists interactions of Bleomycin with, for example, Adenovirus types 4 and 7 live, Brentuximab, Brentuximab vedotin. The full list is on the Bleomycin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
