藥物交互作用
Bortezomib + Etrasimod
嚴重程度: 嚴重
Bortezomib and Etrasimod: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Etrasimod lowers circulating lymphocytes, and bortezomib is an antineoplastic with immunosuppressive effects. Together they may increase the risk of serious infection. The combination has not been formally studied.
用白話說明這項交互作用的意義
Bortezomib and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bortezomib belongs to Oncology; Etrasimod belongs to Gastrointestinal Tract.
為什麼會發生
Additive immunosuppression from S1P receptor modulation (lymphocyte sequestration) plus proteasome inhibitor effects.
處置方式
Avoid concurrent use where possible. If it is necessary, monitor closely for infection and check lymphocyte counts.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Bortezomib 的其他交互作用
Etrasimod 的其他交互作用
常見問題
Can I take Bortezomib with Etrasimod?
MediHelp rates the interaction as major. Bortezomib and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Etrasimod lowers circulating lymphocytes, and bortezomib is an antineoplastic with immunosuppressive effects. Together they may increase the risk of serious infection. The combination has not been formally studied.
How serious is the interaction between Bortezomib and Etrasimod?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use where possible. If it is necessary, monitor closely for infection and check lymphocyte counts.
What other medicines interact with Bortezomib?
MediHelp also lists interactions of Bortezomib with, for example, Apalutamide, Carbamazepine, Fosphenytoin. The full list is on the Bortezomib page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
