藥物交互作用
Cabotegravir + Magnesium hydroxide
嚴重程度: 中度
Cabotegravir and Magnesium hydroxide: moderate interaction.
最後更新
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摘要
Magnesium antacids chelate oral cabotegravir in the gut and may lower its plasma levels, risking reduced antiviral effect. This applies to the oral formulation only.
用白話說明這項交互作用的意義
Cabotegravir and Magnesium hydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cabotegravir belongs to Anti Virals; Magnesium hydroxide belongs to Gastrointestinal Tract.
為什麼會發生
Magnesium cations chelate cabotegravir in the GI tract, reducing absorption.
處置方式
Give the antacid at least 2 hours before or 4 hours after oral cabotegravir.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Magnesium hydroxide 的其他交互作用
Cabotegravir 的其他交互作用
常見問題
Can I take Cabotegravir with Magnesium hydroxide?
MediHelp rates the interaction as moderate. Cabotegravir and Magnesium hydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium antacids chelate oral cabotegravir in the gut and may lower its plasma levels, risking reduced antiviral effect. This applies to the oral formulation only.
How serious is the interaction between Cabotegravir and Magnesium hydroxide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the antacid at least 2 hours before or 4 hours after oral cabotegravir.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
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