藥物交互作用
Carbamazepine + Orlistat
嚴重程度: 中度
Carbamazepine and Orlistat: moderate interaction.
最後更新
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摘要
Orlistat has been linked to reduced antiepileptic levels and breakthrough seizures in case reports, including with carbamazepine. Loss of seizure control could be serious.
用白話說明這項交互作用的意義
Carbamazepine and Orlistat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbamazepine belongs to Central Nervous System; Orlistat belongs to Miscellaneous.
為什麼會發生
Orlistat may reduce carbamazepine absorption from the gut; the mechanism is not firmly established.
處置方式
Monitor carbamazepine levels and seizure frequency when orlistat is started or stopped. Consider avoiding orlistat in patients with poorly controlled epilepsy.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Carbamazepine 的其他交互作用
Orlistat 的其他交互作用
常見問題
Can I take Carbamazepine with Orlistat?
MediHelp rates the interaction as moderate. Carbamazepine and Orlistat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Orlistat has been linked to reduced antiepileptic levels and breakthrough seizures in case reports, including with carbamazepine. Loss of seizure control could be serious.
How serious is the interaction between Carbamazepine and Orlistat?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor carbamazepine levels and seizure frequency when orlistat is started or stopped. Consider avoiding orlistat in patients with poorly controlled epilepsy.
What other medicines interact with Carbamazepine?
MediHelp also lists interactions of Carbamazepine with, for example, Artemether / lumefantrine, Cabotegravir, Delamanid. The full list is on the Carbamazepine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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