藥物交互作用
Cholecalciferol + Orlistat
嚴重程度: 中度
Cholecalciferol and Orlistat: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Orlistat blocks dietary fat digestion and thereby reduces absorption of fat-soluble vitamins, including vitamin D. Long-term use can lower vitamin D levels.
用白話說明這項交互作用的意義
Cholecalciferol and Orlistat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cholecalciferol belongs to Musculoskeletal; Orlistat belongs to Miscellaneous.
為什麼會發生
Inhibition of gastrointestinal lipases reduces fat absorption and micellar solubilization of fat-soluble vitamins.
處置方式
Take vitamin D at least 2 hours before or after orlistat, for example at bedtime. Monitor 25-hydroxyvitamin D levels and adjust the dose as needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cholecalciferol 的其他交互作用
Orlistat 的其他交互作用
常見問題
Can I take Cholecalciferol with Orlistat?
MediHelp rates the interaction as moderate. Cholecalciferol and Orlistat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Orlistat blocks dietary fat digestion and thereby reduces absorption of fat-soluble vitamins, including vitamin D. Long-term use can lower vitamin D levels.
How serious is the interaction between Cholecalciferol and Orlistat?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take vitamin D at least 2 hours before or after orlistat, for example at bedtime. Monitor 25-hydroxyvitamin D levels and adjust the dose as needed.
What other medicines interact with Cholecalciferol?
MediHelp also lists interactions of Cholecalciferol with, for example, Digoxin, Aluminum hydroxide, Calcium acetate. The full list is on the Cholecalciferol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
