藥物交互作用
Cefpodoxime + Didanosine
嚴重程度: 中度
Cefpodoxime and Didanosine: moderate interaction.
最後更新
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摘要
Didanosine chewable tablets and oral solution contain buffering agents that raise gastric pH, and cefpodoxime absorption depends on an acidic environment. Co-administration can lower cefpodoxime exposure and may reduce its efficacy.
用白話說明這項交互作用的意義
Cefpodoxime and Didanosine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefpodoxime belongs to Anti Bacterial; Didanosine belongs to Anti Virals.
為什麼會發生
Buffered didanosine formulations increase gastric pH, reducing dissolution and absorption of cefpodoxime proxetil.
處置方式
Give cefpodoxime at least 2 hours before buffered didanosine formulations. Monitor clinical response to the antibiotic.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cefpodoxime 的其他交互作用
Didanosine 的其他交互作用
常見問題
Can I take Cefpodoxime with Didanosine?
MediHelp rates the interaction as moderate. Cefpodoxime and Didanosine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Didanosine chewable tablets and oral solution contain buffering agents that raise gastric pH, and cefpodoxime absorption depends on an acidic environment. Co-administration can lower cefpodoxime exposure and may reduce its efficacy.
How serious is the interaction between Cefpodoxime and Didanosine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give cefpodoxime at least 2 hours before buffered didanosine formulations. Monitor clinical response to the antibiotic.
What other medicines interact with Cefpodoxime?
MediHelp also lists interactions of Cefpodoxime with, for example, Aluminum hydroxide, Amikacin, Calcium carbonate. The full list is on the Cefpodoxime page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
