藥物交互作用
Cholestyramine + Raloxifene
嚴重程度: 嚴重
Cholestyramine and Raloxifene: major interaction.
最後更新
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摘要
Cholestyramine binds raloxifene in the gut and interrupts its enterohepatic recycling, markedly lowering raloxifene levels. This can reduce raloxifene efficacy.
用白話說明這項交互作用的意義
Cholestyramine and Raloxifene can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cholestyramine belongs to Cardiovascular; Raloxifene belongs to Endocrine.
為什麼會發生
Bile acid sequestrant binds raloxifene and blocks absorption and enterohepatic recirculation.
處置方式
Avoid concurrent use as raloxifene labeling advises. If unavoidable, consider an alternative to one drug.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Raloxifene 的其他交互作用
Cholestyramine 的其他交互作用
常見問題
Can I take Cholestyramine with Raloxifene?
MediHelp rates the interaction as major. Cholestyramine and Raloxifene can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cholestyramine binds raloxifene in the gut and interrupts its enterohepatic recycling, markedly lowering raloxifene levels. This can reduce raloxifene efficacy.
How serious is the interaction between Cholestyramine and Raloxifene?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use as raloxifene labeling advises. If unavoidable, consider an alternative to one drug.
What other medicines interact with Raloxifene?
MediHelp also lists interactions of Raloxifene with, for example, Ospemifene, Apalutamide, Levothyroxine. The full list is on the Raloxifene page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
