藥物交互作用
Eluxadoline + Oxymorphone
嚴重程度: 嚴重
Eluxadoline and Oxymorphone: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Eluxadoline is used for diarrhea-predominant IBS and can cause constipation and pancreatitis-related complications. Opioids worsen constipation, raising the risk of serious constipation-related events.
用白話說明這項交互作用的意義
Eluxadoline and Oxymorphone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Eluxadoline belongs to Gastrointestinal Tract; Oxymorphone belongs to Musculoskeletal.
為什麼會發生
Additive reduction in gastrointestinal motility via opioid receptor activity in the gut.
處置方式
Avoid the combination where feasible; if constipation develops, stop eluxadoline and manage it. Monitor bowel function.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Oxymorphone 的其他交互作用
Eluxadoline 的其他交互作用
常見問題
Can I take Eluxadoline with Oxymorphone?
MediHelp rates the interaction as major. Eluxadoline and Oxymorphone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Eluxadoline is used for diarrhea-predominant IBS and can cause constipation and pancreatitis-related complications. Opioids worsen constipation, raising the risk of serious constipation-related events.
How serious is the interaction between Eluxadoline and Oxymorphone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where feasible; if constipation develops, stop eluxadoline and manage it. Monitor bowel function.
What other medicines interact with Oxymorphone?
MediHelp also lists interactions of Oxymorphone with, for example, Alvimopan, Ethanol, Isocarboxazid. The full list is on the Oxymorphone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
