藥物交互作用
Flutamide + Telotristat etiprate
嚴重程度: 中度
Flutamide and Telotristat etiprate: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Flutamide is a CES2 substrate and telotristat may alter carboxylesterase handling of it, so flutamide exposure could change. The clinical consequence is uncertain, but flutamide carries a risk of liver toxicity.
用白話說明這項交互作用的意義
Flutamide and Telotristat etiprate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Flutamide belongs to Endocrine; Telotristat etiprate belongs to Gastrointestinal Tract.
為什麼會發生
Possible modulation of CES2-mediated metabolism of flutamide; not well characterized clinically.
處置方式
Monitor liver function tests and clinical response to flutamide when telotristat is started or stopped.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Telotristat etiprate 的其他交互作用
Flutamide 的其他交互作用
常見問題
Can I take Flutamide with Telotristat etiprate?
MediHelp rates the interaction as moderate. Flutamide and Telotristat etiprate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Flutamide is a CES2 substrate and telotristat may alter carboxylesterase handling of it, so flutamide exposure could change. The clinical consequence is uncertain, but flutamide carries a risk of liver toxicity.
How serious is the interaction between Flutamide and Telotristat etiprate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor liver function tests and clinical response to flutamide when telotristat is started or stopped.
What other medicines interact with Telotristat etiprate?
MediHelp also lists interactions of Telotristat etiprate with, for example, Bupropion, Capecitabine, Everolimus. The full list is on the Telotristat etiprate page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
