藥物交互作用
Fluvastatin + Niacin
嚴重程度: 中度
Fluvastatin and Niacin: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Lipid-modifying doses of niacin given with a statin may add to the risk of myopathy and rarely rhabdomyolysis. The risk appears greatest at high niacin doses and in patients with renal impairment or advanced age.
用白話說明這項交互作用的意義
Fluvastatin and Niacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fluvastatin belongs to Cardiovascular; Niacin belongs to Cardiovascular.
為什麼會發生
Additive myotoxicity; niacin may also contribute to muscle injury through an unclear mechanism.
處置方式
Use the lowest effective doses and educate the patient to report muscle pain, weakness or dark urine. Check CK and renal function if symptoms develop.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Fluvastatin 的其他交互作用
Niacin 的其他交互作用
常見問題
Can I take Fluvastatin with Niacin?
MediHelp rates the interaction as moderate. Fluvastatin and Niacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lipid-modifying doses of niacin given with a statin may add to the risk of myopathy and rarely rhabdomyolysis. The risk appears greatest at high niacin doses and in patients with renal impairment or advanced age.
How serious is the interaction between Fluvastatin and Niacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective doses and educate the patient to report muscle pain, weakness or dark urine. Check CK and renal function if symptoms develop.
What other medicines interact with Fluvastatin?
MediHelp also lists interactions of Fluvastatin with, for example, Cyclosporine, Cyclosporin, Gemfibrozil. The full list is on the Fluvastatin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
