藥物交互作用
Panobinostat + Pimozide
嚴重程度: 禁忌併用
Panobinostat and Pimozide: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Both drugs prolong the QT interval, so combining them raises the risk of torsades de pointes and other serious arrhythmias. Panobinostat labeling advises against use with QT-prolonging drugs.
用白話說明這項交互作用的意義
Panobinostat and Pimozide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Panobinostat belongs to Oncology; Pimozide belongs to Central Nervous System.
為什麼會發生
Additive prolongation of cardiac repolarization (QT interval).
處置方式
Do not use together; choose an alternative to pimozide during panobinostat therapy. Keep potassium and magnesium within normal range and monitor ECG if any QT-prolonging drug is required.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pimozide 的其他交互作用
Panobinostat 的其他交互作用
常見問題
Can I take Panobinostat with Pimozide?
MediHelp rates the interaction as contraindicated. Panobinostat and Pimozide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs prolong the QT interval, so combining them raises the risk of torsades de pointes and other serious arrhythmias. Panobinostat labeling advises against use with QT-prolonging drugs.
How serious is the interaction between Panobinostat and Pimozide?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; choose an alternative to pimozide during panobinostat therapy. Keep potassium and magnesium within normal range and monitor ECG if any QT-prolonging drug is required.
What other medicines interact with Pimozide?
MediHelp also lists interactions of Pimozide with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Pimozide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
