Drug reference
domperidone
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Gastrointestinal Tract (Prokinetic)
Mechanism of action
Domperidone is a dopamine antagonist with anti-emetic properties, Domperidone does not readily cross the blood-brain barrier. Domperidone promotes the release of prolactin from the pituitary.
Common side effects
- Dry mouth
- Somnolence
- Headache
- Diarrhea
Known interactions (8)
- Azithromycin + domperidone Contraindicated
- domperidone + erythromycin Major
- Dexlansoprazole + domperidone Moderate
- domperidone + lansoprazole Moderate
- domperidone + omeprazole Moderate
- domperidone + pantoprazole Moderate
- domperidone + Polyethylene Glycol 3350 Moderate
- domperidone + rabeprazole Moderate
Related conditions
Frequently asked questions
What drug class is domperidone?
domperidone belongs to: Gastrointestinal Tract.
How does domperidone work?
Domperidone is a dopamine antagonist with anti-emetic properties, Domperidone does not readily cross the blood-brain barrier. Domperidone promotes the release of prolactin from the pituitary.
What are the common side effects of domperidone?
Dry mouth, Somnolence, Headache, Diarrhea
Which drugs interact with domperidone?
Azithromycin, erythromycin, Dexlansoprazole, lansoprazole, omeprazole, pantoprazole, Polyethylene Glycol 3350, rabeprazole
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