Drug interactions
Bumetanide + Maraviroc
Severity: Moderate
Bumetanide and Maraviroc: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc can cause postural hypotension, and bumetanide's volume depletion may add to this effect. Patients with renal impairment are at particular risk of dizziness and syncope.
What this interaction means in plain words
Bumetanide and Maraviroc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bumetanide belongs to Cardiovascular; Maraviroc belongs to Anti Virals.
Why it happens
Additive pharmacodynamic hypotensive effects; maraviroc is not known to alter bumetanide kinetics.
What to do
Monitor orthostatic blood pressure and renal function, especially at initiation. Reduce the diuretic dose or correct volume depletion if symptomatic.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Bumetanide
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Bumetanide with Maraviroc?
MediHelp rates the interaction as moderate. Bumetanide and Maraviroc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Maraviroc can cause postural hypotension, and bumetanide's volume depletion may add to this effect. Patients with renal impairment are at particular risk of dizziness and syncope.
How serious is the interaction between Bumetanide and Maraviroc?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor orthostatic blood pressure and renal function, especially at initiation. Reduce the diuretic dose or correct volume depletion if symptomatic.
What other medicines interact with Bumetanide?
MediHelp also lists interactions of Bumetanide with, for example, Amifostine, Amikacin, Captopril-hydrochlorothiazide. The full list is on the Bumetanide page.
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