Drug interactions
Cetirizine + Elagolix
Severity: Minor
Cetirizine and Elagolix: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Elagolix can inhibit intestinal P-glycoprotein and may raise cetirizine exposure. The practical effect is probably limited to mildly increased antihistamine adverse effects.
What this interaction means in plain words
Cetirizine and Elagolix have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cetirizine belongs to Respiratory; Elagolix belongs to Musculoskeletal.
Why it happens
P-glycoprotein inhibition reduces cetirizine efflux.
What to do
Monitor for increased drowsiness; no empiric dose adjustment is usually required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cetirizine
- Acrivastine + Cetirizine Moderate
- Amisulpride + Cetirizine Moderate
- Asenapine + Cetirizine Moderate
- Avapritinib + Cetirizine Moderate
- Benzhydrocodone / acetaminophen + Cetirizine Moderate
- Brexpiprazole + Cetirizine Moderate
Other interactions of Elagolix
- Cyclosporin + Elagolix Contraindicated
- Elagolix + Gemfibrozil Contraindicated
- Desogestrel-ethinyl estradiol + Elagolix Major
- Elagolix + Erythromycin Major
- Elagolix + Ethinyl estradiol-drospirenone Major
- Elagolix + Ethinyl estradiol-levonorgestrel Major
Frequently asked questions
Can I take Cetirizine with Elagolix?
MediHelp rates the interaction as minor. Cetirizine and Elagolix have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Elagolix can inhibit intestinal P-glycoprotein and may raise cetirizine exposure. The practical effect is probably limited to mildly increased antihistamine adverse effects.
How serious is the interaction between Cetirizine and Elagolix?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for increased drowsiness; no empiric dose adjustment is usually required.
What other medicines interact with Cetirizine?
MediHelp also lists interactions of Cetirizine with, for example, Acrivastine, Amisulpride, Asenapine. The full list is on the Cetirizine page.
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