Drug interactions
Cisapride + Ruxolitinib
Severity: Minor
Cisapride and Ruxolitinib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ruxolitinib is a CYP3A4 substrate, and cisapride is not a meaningful CYP3A4 inhibitor. The legacy direction of effect is not supported, and no important interaction is expected.
What this interaction means in plain words
Cisapride and Ruxolitinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cisapride belongs to Gastrointestinal Tract; Ruxolitinib belongs to Oncology.
Why it happens
No established mechanism; cisapride does not inhibit CYP3A4 to a relevant degree.
What to do
No action is needed beyond routine monitoring of ruxolitinib response and blood counts.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cisapride
- Apomorphine + Cisapride Contraindicated
- Artemether + Cisapride Contraindicated
- Azithromycin + Cisapride Contraindicated
- Ceritinib + Cisapride Contraindicated
- Chloroquine + Cisapride Contraindicated
- Cisapride + Citalopram Contraindicated
Other interactions of Ruxolitinib
Frequently asked questions
Can I take Cisapride with Ruxolitinib?
MediHelp rates the interaction as minor. Cisapride and Ruxolitinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ruxolitinib is a CYP3A4 substrate, and cisapride is not a meaningful CYP3A4 inhibitor. The legacy direction of effect is not supported, and no important interaction is expected.
How serious is the interaction between Cisapride and Ruxolitinib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed beyond routine monitoring of ruxolitinib response and blood counts.
What other medicines interact with Cisapride?
MediHelp also lists interactions of Cisapride with, for example, Apomorphine, Artemether, Azithromycin. The full list is on the Cisapride page.
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