Drug interactions
Dasiglucagon + Sotalol
Severity: Minor
Dasiglucagon and Sotalol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucagon analogues can transiently raise heart rate and blood pressure through catecholamine release. Beta-blockers may blunt this response, and nonselective beta-blockade can also lead to unopposed alpha effects with a transient rise in blood pressure.
What this interaction means in plain words
Dasiglucagon and Sotalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dasiglucagon belongs to Endocrine; Sotalol belongs to Cardiovascular.
Why it happens
Beta-blockade antagonizes catecholamine-mediated effects of dasiglucagon; the glycemic effect is largely preserved.
What to do
Monitor heart rate and blood pressure after dasiglucagon, and recheck glucose as usual.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sotalol
- Arsenic trioxide + Sotalol Contraindicated
- Artemether / lumefantrine + Sotalol Contraindicated
- Disopyramide + Sotalol Contraindicated
- Dofetilide + Sotalol Contraindicated
- Dronedarone + Sotalol Contraindicated
- Droperidol + Sotalol Contraindicated
Other interactions of Dasiglucagon
- Atenolol + Dasiglucagon Moderate
- Dasiglucagon + Esmolol Moderate
- Dasiglucagon + Propranolol Moderate
- Dasiglucagon + Timolol Moderate
- Dasiglucagon + Warfarin Moderate
- Atenolol-chlorthalidone + Dasiglucagon Minor
Frequently asked questions
Can I take Dasiglucagon with Sotalol?
MediHelp rates the interaction as minor. Dasiglucagon and Sotalol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glucagon analogues can transiently raise heart rate and blood pressure through catecholamine release. Beta-blockers may blunt this response, and nonselective beta-blockade can also lead to unopposed alpha effects with a transient rise in blood pressure.
How serious is the interaction between Dasiglucagon and Sotalol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure after dasiglucagon, and recheck glucose as usual.
What other medicines interact with Sotalol?
MediHelp also lists interactions of Sotalol with, for example, Arsenic trioxide, Artemether / lumefantrine, Disopyramide. The full list is on the Sotalol page.
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