Drug interactions
Elagolix + Ixazomib
Severity: Minor
Elagolix and Ixazomib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Elagolix is a weak-to-moderate CYP3A inducer and may reduce ixazomib exposure. The effect is likely modest, but it could slightly weaken ixazomib's anticancer activity.
What this interaction means in plain words
Elagolix and Ixazomib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Elagolix belongs to Musculoskeletal; Ixazomib belongs to Oncology.
Why it happens
Elagolix induces CYP3A4, increasing ixazomib metabolism.
What to do
No empirical ixazomib dose change is recommended; monitor disease response during coadministration.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ixazomib
- Apalutamide + Ixazomib Major
- Carbamazepine + Ixazomib Major
- Dabrafenib + Ixazomib Major
- Enzalutamide + Ixazomib Major
- Etrasimod + Ixazomib Major
- Fosphenytoin + Ixazomib Major
Other interactions of Elagolix
- Cyclosporin + Elagolix Contraindicated
- Elagolix + Gemfibrozil Contraindicated
- Desogestrel-ethinyl estradiol + Elagolix Major
- Elagolix + Erythromycin Major
- Elagolix + Ethinyl estradiol-drospirenone Major
- Elagolix + Ethinyl estradiol-levonorgestrel Major
Frequently asked questions
Can I take Elagolix with Ixazomib?
MediHelp rates the interaction as minor. Elagolix and Ixazomib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Elagolix is a weak-to-moderate CYP3A inducer and may reduce ixazomib exposure. The effect is likely modest, but it could slightly weaken ixazomib's anticancer activity.
How serious is the interaction between Elagolix and Ixazomib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No empirical ixazomib dose change is recommended; monitor disease response during coadministration.
What other medicines interact with Ixazomib?
MediHelp also lists interactions of Ixazomib with, for example, Apalutamide, Carbamazepine, Dabrafenib. The full list is on the Ixazomib page.
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